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Find cheap one-way flights from Sao Paulo to Santiago starting at US$51.

For as little as US$51, you can take your next adventure to Santiago without breaking the bank. Choose between one-way and return tickets from Sao Paulo below.

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Sao Paulo to Santiago Flight time & Schedules

Flight info.
Departure
Arrival
Weekly Schedule
  1. H2601

    05:50

    GRU

    4.3h

    Nonstop

    10:10

    SCL

    S--W---
  2. LA713

    07:10

    GRU

    4.3h

    Nonstop

    10:30

    SCL

    ---W---
  3. LA715

    07:10

    GRU

    4.3h

    Nonstop

    10:30

    SCL

    SMT-TFS
  4. H2605

    08:50

    GRU

    4.3h

    Nonstop

    13:10

    SCL

    SMTWTFS
  5. LA627

    09:55

    GRU

    4.3h

    Nonstop

    13:15

    SCL

    SMT-T--
  6. H2651

    10:25

    GRU

    4.4h

    Nonstop

    13:50

    SCL

    ---W-F-
  7. LA8104

    10:50

    GRU

    4.4h

    Nonstop

    14:15

    SCL

    ---W-F-
  8. LA8096

    16:10

    GRU

    4.3h

    Nonstop

    19:30

    SCL

    SMTWTFS
  9. LA8030

    23:40

    GRU

    4.3h

    Nonstop

    03:00

    SCL

    SMTW-FS

When is the cheapest time to book flights from Sao Paulo to Santiago?

Explore the best time to buy affordable tickets to Santiago with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Cheapest airlines flights from Sao Paulo to Santiago

Which airline provides the cheapest flights from Sao Paulo to Santiago? Discover the option that best suits your travel needs before embarking on your journey.

Frequently Asked Questions

  • When are flight tickets from Sao Paulo (SAO) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from Sao Paulo to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Sao Paulo (SAO) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around $204.
  • How long does it take to fly from Sao Paulo (SAO) to Santiago (SCL) and what is the distance?

    It takes around 4 hours 21 minutes to fly from Sao Paulo (SAO) to Santiago (SCL).
  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 12 km. It takes about 30 minutes by taxi.
  • What are the most popular airlines that fly from Sao Paulo (SAO) to Santiago (SCL)?

    Airlines with flights from Sao Paulo (SAO) to Santiago (SCL): JetSMART Airlines, LATAM Airlines, Delta Air Lines and Sky Airline.

How to find a cheap flight from Sao Paulo to Santiago

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Being flexible with your dates to get the cheapest Sao Paulo to Santiago ticket.
Tap "Date" on flight search bar to scan through the calender for Sao Paulo to Santiago airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Fri, Apr 11 at US$51 for one-way flights.
2
Compare cheap Sao Paulo to Santiago flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Sao Paulo to Santiago. The cheapest airline operating is Sky Airline.
3
Set up a Price Alert
By setting up a Price Alert for your Sao Paulo to Santiago route, you can easily track the price of your airline tickets from Sao Paulo to Santiago without manually checking every day.
4
Don't miss cheap Sao Paulo to Santiago flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com free app and search for cheap flight tickets from Sao Paulo to Santiago to get exclusive deals for you.

Sao Paulo to Santiago Flight Information

Cheapest nonstop flight price$51
Cheapest round-trip ticket price$132
Off-season for travelJanuary
Peak season for travelNovember
Flight distance2,595.22 km
Average flight time4 hours 21 minutes
Popular airlineSky Airline