Find cheap one-way flights from Santa Maria to Brussels starting at US$209.

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

Round-trip
One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to book flights from Santa Maria to Brussels?

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights

From price

16 23
23 30
Apr

30 6
6 13
13 20
20 27
May

27 4
4 11
11 18
18 25
Jun

25 1
1 8

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

When are flight tickets from Santa Maria (SMA) to Brussels (BRU) the cheapest?

Airlines adjust prices for flights from Santa Maria to Brussels based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Santa Maria (SMA) to Brussels (BRU) cost?

According to Trip.com's data, the lowest price is around $315.
What is the transportation method from the main airport to downtown in Brussels?
- The distance from Brussels International Airport to downtown is about 10 km. It takes about 30 minutes by taxi.
- The distance from Brussels South Charleroi Airport to downtown is about 43 km. It takes about 1 hour by taxi.

How to find a cheap flight from Santa Maria to Brussels

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santa Maria to Brussels. Book your flights at the right time and save more.

Being flexible with your dates to get the cheapest Santa Maria to Brussels ticket.

Tap "Date" on flight search bar to scan through the calender for Santa Maria to Brussels airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Sun, Apr 13 at US$209 for one-way flights.

Compare cheap Santa Maria to Brussels flight deals from over hundreds of airlines.

Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Santa Maria to Brussels. The cheapest airline operating is Azores Airlines.

Set up a Price Alert

By setting up a Price Alert for your Santa Maria to Brussels route, you can easily track the price of your airline tickets from Santa Maria to Brussels without manually checking every day.

Don't miss cheap Santa Maria to Brussels flight deals and promo codes.

You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights for cheap flights. If registering a free membership, you can receive more deals for your flights.

Book early or wait unitl the last minute.

It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.

Search for flights on the go.

To get the best flight booking experience on the go, download Trip.com free app and search for cheap flight tickets from Santa Maria to Brussels to get exclusive deals for you.

Santa Maria to Brussels Flight Information

Cheapest one-way flight price	$208
Off-season for travel	June
Peak season for travel	April
Flight distance	2,805.4 km
Popular airline	Azores Airlines