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Find cheap one-way flights from San Francisco to Prague starting at US$304.

Discover our range of affordable one-way and round-trip flights from San Francisco to Prague and kick-start your next adventure today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

San Francisco to Prague Flight time & Schedules

Flight info.
Departure
Arrival
Weekly Schedule
  1. AC760

    08:15

    SFO

    5.7h

    16:55

    YUL

    SMTWTFS
  2. AC894

    20:25

    YUL

    7.9h

    10:20

    MXP

    --T--F-
  3. U23903

    11:50

    MXP

    1.5h

    13:20

    PRG

    S--WTFS
  4. AA2093

    10:20

    SFO

    3.4h

    15:44

    DFW

    SMTWTFS
  5. AA050

    16:20

    DFW

    9.0h

    07:20

    LHR

    SMTWTFS
  6. U22635

    17:30

    LTN

    2.0h

    20:30

    PRG

    S-TWT-S
  7. UA8828

    14:40

    SFO

    10.8h

    10:25

    FRA

    SMTWTFS
  8. LH5668

    16:20

    FRA

    1.3h

    17:35

    LIN

    SMTWTFS
  9. U23905

    15:45

    MXP

    1.5h

    17:15

    PRG

    SMTWTFS
  10. BA284

    16:20

    SFO

    10.6h

    10:55

    LHR

    SMT--FS
  11. BA584

    20:45

    LHR

    2.0h

    23:45

    MXP

    SMTWTFS
  12. U23905

    15:45

    MXP

    1.5h

    17:15

    PRG

    SMTWTFS
  13. BA286

    19:20

    SFO

    10.4h

    13:45

    LHR

    SMTWTFS
  14. BA570

    18:50

    LHR

    2.0h

    21:50

    LIN

    SMTWTFS
  15. U23909

    06:55

    MXP

    1.5h

    08:25

    PRG

    S--W---
  16. BF711

    20:30

    SFO

    10.8h

    16:20

    ORY

    S--W---
  17. TO4398

    14:50

    ORY

    1.7h

    16:30

    PRG

    SMTWT-S
  18. LH459

    21:05

    SFO

    11.1h

    17:10

    MUC

    SMTWTFS
  19. LH9514

    17:45

    MUC

    1.2h

    18:55

    MXP

    SMTWTF-
  20. W46331

    06:10

    MXP

    1.5h

    07:40

    PRG

    -M--TFS
  21. UA8882

    21:05

    SFO

    11.1h

    17:10

    MUC

    SM-WTFS
  22. LH9514

    17:45

    MUC

    1.2h

    18:55

    MXP

    SMTWTF-
  23. W46331

    06:10

    MXP

    1.5h

    07:40

    PRG

    -M--TFS
  24. LH459

    21:05

    SFO

    11.1h

    17:10

    MUC

    SMTWTFS
  25. LH7432

    22:05

    MUC

    1.2h

    23:15

    MXP

    SMTWT-S
  26. W46331

    06:10

    MXP

    1.5h

    07:40

    PRG

    -M--TFS
  27. LH459

    21:05

    SFO

    11.1h

    17:10

    MUC

    SMTWTFS
  28. LH1862

    22:05

    MUC

    1.2h

    23:15

    MXP

    SMTWT-S
  29. W46331

    06:10

    MXP

    1.5h

    07:40

    PRG

    -M--TFS

When is the cheapest time to book flights from San Francisco to Prague?

These price trend charts carefully monitor and predict how flight prices from San Francisco to Prague will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Cheapest airlines flights from San Francisco to Prague

Which airline provides the cheapest flights from San Francisco to Prague? Discover the option that best suits your travel needs before embarking on your journey.

Frequently Asked Questions

  • When are flight tickets from San Francisco (SFO) to Prague (PRG) the cheapest?

    Airlines adjust prices for flights from San Francisco to Prague based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from San Francisco (SFO) to Prague (PRG) cost?

    According to Trip.com's data, the lowest price is around $1,373.
  • What is the transportation method from the main airport to downtown in Prague?

    • The distance from Vaclav Havel Airport to downtown is about 12 km. It takes about 30 minutes by taxi.

How to find a cheap flight from San Francisco to Prague

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Being flexible with your dates to get the cheapest San Francisco to Prague ticket.
Tap "Date" on flight search bar to scan through the calender for San Francisco to Prague airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Sat, Mar 1 at US$304 for one-way flights.
2
Compare cheap San Francisco to Prague flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from San Francisco to Prague. The cheapest airline operating is French Bee Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your San Francisco to Prague route, you can easily track the price of your airline tickets from San Francisco to Prague without manually checking every day.
4
Don't miss cheap San Francisco to Prague flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com free app and search for cheap flight tickets from San Francisco to Prague to get exclusive deals for you.

San Francisco to Prague Flight Information

Cheapest nonstop flight price$303
Off-season for travelJanuary
Peak season for travelNovember
Flight distance9,376.93 km
Popular airlineAmerican Airlines