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Flights from Pensacola to Des Moines
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Find cheap one-way flights from Pensacola to Des Moines starting at US$177.

Discover our range of affordable one-way and round-trip flights from Pensacola to Des Moines and kick-start your next adventure today!

  • One way
  • Round-trip
      • PNS12:32
        5h 4m
        1 stop
        DSM17:36
        Thu, Feb 13|Pensacola - Des Moines|Delta Air Lines
        US$177US$377
        53% OFF
        53% OFF
        US$377US$177

        Choose Delta Air Lines flights from Pensacola to Des Moines.The one-way connecting flight with Delta Air Lines departs from Pensacola International Airport on Thu, Feb 13, arriving at Des Moines International Airport.One-way Prices start from US$177 including taxes and charges.

      • PNS18:03
        4h 47m
        1 stop
        DSM22:50
        Mon, Jan 13|Pensacola - Des Moines|Delta Air Lines
        US$188US$377
        50% OFF
        50% OFF
        US$377US$188

        Choose Delta Air Lines flights from Pensacola to Des Moines.The one-way connecting flight with Delta Air Lines departs from Pensacola International Airport on Mon, Jan 13, arriving at Des Moines International Airport.One-way Prices start from US$188 including taxes and charges.

      • PNS06:00
        4h 45m
        1 stop
        DSM10:45
        Fri, Jan 31|Pensacola - Des Moines|Delta Air Lines
        US$195US$377
        48% OFF
        48% OFF
        US$377US$195

        Choose Delta Air Lines flights from Pensacola to Des Moines.The one-way connecting flight with Delta Air Lines departs from Pensacola International Airport on Fri, Jan 31, arriving at Des Moines International Airport.One-way Prices start from US$195 including taxes and charges.

      • PNS15:10
        7h 20m
        1 stop
        DSM22:30
        Thu, Feb 13|Pensacola - Des Moines|United Airlines
        US$208
        US$208

        Choose United Airlines flights from Pensacola to Des Moines.The one-way connecting flight with United Airlines departs from Pensacola International Airport on Thu, Feb 13, arriving at Des Moines International Airport.One-way Prices start from US$208 including taxes and charges.

      • PNS11:38
        5h 11m
        1 stop
        DSM16:49
        Thu, Feb 13|Pensacola - Des Moines|American Airlines
        US$211
        US$211

        Choose American Airlines flights from Pensacola to Des Moines.The one-way connecting flight with American Airlines departs from Pensacola International Airport on Thu, Feb 13, arriving at Des Moines International Airport.One-way Prices start from US$211 including taxes and charges.

      • PNS16:55
        5h 35m
        1 stop
        DSM22:30
        Mon, Jan 13|Pensacola - Des Moines|United Airlines
        US$227
        US$227

        Choose United Airlines flights from Pensacola to Des Moines.The one-way connecting flight with United Airlines departs from Pensacola International Airport on Mon, Jan 13, arriving at Des Moines International Airport.One-way Prices start from US$227 including taxes and charges.

      • PNS07:00
        7h 15m
        1 stop
        DSM14:15
        Fri, Jan 31|Pensacola - Des Moines|United Airlines
        US$229
        US$229

        Choose United Airlines flights from Pensacola to Des Moines.The one-way connecting flight with United Airlines departs from Pensacola International Airport on Fri, Jan 31, arriving at Des Moines International Airport.One-way Prices start from US$229 including taxes and charges.

      • PNS06:00
        4h 40m
        1 stop
        DSM10:40
        Sun, Mar 2|Pensacola - Des Moines|Delta Air Lines
        US$293
        US$293

        Choose Delta Air Lines flights from Pensacola to Des Moines.The one-way connecting flight with Delta Air Lines departs from Pensacola International Airport on Sun, Mar 2, arriving at Des Moines International Airport.One-way Prices start from US$293 including taxes and charges.

      • PNS14:33
        6h 50m
        1 stop
        DSM21:23
        Sun, Mar 2|Pensacola - Des Moines|United Airlines
        US$320
        US$320

        Choose United Airlines flights from Pensacola to Des Moines.The one-way connecting flight with United Airlines departs from Pensacola International Airport on Sun, Mar 2, arriving at Des Moines International Airport.One-way Prices start from US$320 including taxes and charges.

      • PNS01:00 pm
        3h 5m
        Nonstop
        DSM02:00 pm
        Sun, Jan 19|Pensacola - Des Moines|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to book flights from Pensacola to Des Moines?

These price trend charts carefully monitor and predict how flight prices from Pensacola to Des Moines will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Cheapest airlines flights from Pensacola to Des Moines

We have a range of prices from different airlines providing flights from Pensacola to Des Moines. Check below for the journey which best suits your travel needs.

Delta Air Lines
From US$177
United Airlines
From US$208
American Airlines
From US$211
Frontier Airlines
From US$296
Spirit Airlines
From US$344

Find more flights and airlines

Find cheap flights from Pensacola to Des Moines by different airports

Did you know that you can save money and time on an alternative route from Pensacola to Des Moines? Check out some of the different available routes below.

  • Cheapest
    Delta Air Lines
    PNS
    12:32
    5h 4m
    1 transfer
    DSM
    17:36
    Pensacola International Airport - Des Moines International Airport
    Thu, Feb 13Delta Air Lines
    US$177
  • Delta Air Lines
    PNS
    12:32
    5h 4m
    1 transfer
    DSM
    17:36
    Pensacola International Airport - Des Moines International Airport
    Thu, Feb 13Delta Air Lines
    US$177
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Pensacola (PNS) to Des Moines (DSM) the cheapest?

    Airlines adjust prices for flights from Pensacola to Des Moines based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Pensacola (PNS) to Des Moines (DSM) cost?

    According to Trip.com's data, the lowest price is around $418.

How to find a cheap flight from Pensacola to Des Moines

If you don’t know some of the key things to look out for when buying flight tickets, prices can often end up sky high or, worse, sold out! We’ve carefully compiled our six most important steps to help ensure you’re getting the best deals when planning your next journey.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Pensacola to Des Moines Flight Information

Cheapest nonstop flight price$176
Off-season for travelDecember
Peak season for travelOctober
Flight distance1,360.47 km
Popular airlineDelta Air Lines

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