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Find cheap one-way flights from Knoxville to Roanoke starting at US$343.

Whether you’re going for a one-way or round-trip to Roanoke, we’ve got you covered! Check out these different flight options from Knoxville below.

  • One way
  • Round-trip
      • TYS14:35
        4h 20m
        1 stop
        ROA18:55
        Tue, Jan 14|Knoxville - Roanoke|United Airlines
        US$343US$766
        55% OFF
        55% OFF
        US$766US$343

        Choose United Airlines flights from Knoxville to Roanoke.The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Tue, Jan 14, arriving at Roanoke Regional Airport.One-way Prices start from US$343 including taxes and charges.

      • TYS05:45
        4h 58m
        1 stop
        ROA10:43
        Tue, Jan 14|Knoxville - Roanoke|Delta Air Lines
        US$343US$766
        55% OFF
        55% OFF
        US$766US$343

        Choose Delta Air Lines flights from Knoxville to Roanoke.The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Tue, Jan 14, arriving at Roanoke Regional Airport.One-way Prices start from US$343 including taxes and charges.

      • TYS19:17
        4h 42m
        1 stop
        ROA23:59
        Mon, Jan 20|Knoxville - Roanoke|Delta Air Lines
        US$504US$766
        34% OFF
        34% OFF
        US$766US$504

        Choose Delta Air Lines flights from Knoxville to Roanoke.The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Mon, Jan 20, arriving at Roanoke Regional Airport.One-way Prices start from US$504 including taxes and charges.

      • TYS06:30
        9h 33m
        1 stop
        ROA16:03
        Tue, Jan 14|Knoxville - Roanoke|American Airlines
        US$605
        US$605

        Choose American Airlines flights from Knoxville to Roanoke.The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Tue, Jan 14, arriving at Roanoke Regional Airport.One-way Prices start from US$605 including taxes and charges.

      • TYS01:00 pm
        3h 5m
        Nonstop
        ROA02:00 pm
        Mon, Jan 20|Knoxville - Roanoke|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to book flights from Knoxville to Roanoke?

Explore the best time to buy affordable tickets to Roanoke with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap flights from Knoxville to Roanoke by different airports

Searching for potential routes that might be cheaper and faster? There are a few alternative ways to get to Roanoke from Knoxville which could help you save money and time.

  • Cheapest
    Delta Air Lines
    TYS
    19:17
    4h 42m
    2 transfer
    ROA
    23:59
    Mcghee Tyson Airport - Roanoke Regional Airport
    Tue, Jan 21Delta Air Lines
    US$202
  • Delta Air Lines
    TYS
    19:17
    4h 42m
    2 transfer
    ROA
    23:59
    Mcghee Tyson Airport - Roanoke Regional Airport
    Tue, Jan 21Delta Air Lines
    US$202
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Knoxville (TYS) to Roanoke (ROA) the cheapest?

    Airlines adjust prices for flights from Knoxville to Roanoke based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Knoxville (TYS) to Roanoke (ROA) cost?

    According to Trip.com's data, the lowest price is around $351.

How to find a cheap flight from Knoxville to Roanoke

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Knoxville to Roanoke Flight Information

Cheapest nonstop flight price$342
Off-season for travelDecember
Peak season for travelOctober
Flight distance396.38 km
Popular airlineAmerican Airlines

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