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Find cheap one-way flights from Cali to Panama City starting at US$104.

Whether you’re going for a one-way or round-trip to Panama City, we’ve got you covered! Check out these different flight options from Cali below.

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Cali to Panama City Flight time & Schedules

Flight info.
Departure
Arrival
Weekly Schedule
  1. CM322

    04:41

    CLO

    1.6h

    Nonstop

    06:14

    PTY

    SMTWTFS
  2. CM842

    08:47

    CLO

    1.6h

    Nonstop

    10:20

    PTY

    SMTWTFS
  3. CM308

    11:59

    CLO

    1.6h

    Nonstop

    13:32

    PTY

    SM-W-FS
  4. CM247

    15:21

    CLO

    1.6h

    Nonstop

    16:54

    PTY

    SMTWTFS
  5. AV9274

    15:37

    CLO

    0.9h

    16:29

    MDE

    S-T-T-S
  6. AV316

    17:55

    MDE

    1.3h

    19:15

    PTY

    SM--T-S
  7. AV9202

    15:41

    CLO

    1.1h

    16:44

    BOG

    S-T-T-S
  8. AV056

    19:25

    BOG

    1.8h

    21:10

    PTY

    SMTWTFS
  9. AV9816

    17:31

    CLO

    1.0h

    18:32

    BOG

    SMTWTFS
  10. AV056

    19:25

    BOG

    1.8h

    21:10

    PTY

    SMTWTFS
  11. AV9224

    20:16

    CLO

    1.0h

    21:15

    BOG

    SMTWTFS
  12. AV040

    22:25

    BOG

    1.8h

    00:10

    PTY

    SMTWTFS
  13. AV9812

    20:40

    CLO

    1.0h

    21:39

    BOG

    SMTWTFS
  14. AV040

    22:25

    BOG

    1.8h

    00:10

    PTY

    SMTWTFS
  15. AV9236

    20:55

    CLO

    1.0h

    21:53

    BOG

    SMTWTFS
  16. AV040

    22:25

    BOG

    1.8h

    00:10

    PTY

    SMTWTFS

When is the cheapest time to book flights from Cali to Panama City?

These price trend charts carefully monitor and predict how flight prices from Cali to Panama City will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Cali (CLO) to Panama City (PTY) the cheapest?

    Airlines adjust prices for flights from Cali to Panama City based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Cali (CLO) to Panama City (PTY) cost?

    According to Trip.com's data, the lowest price is around $230.
  • How long does it take to fly from Cali (CLO) to Panama City (PTY) and what is the distance?

    It takes around 1 hour 33 minutes to fly from Cali (CLO) to Panama City (PTY).
  • What is the transportation method from the main airport to downtown in Panama City?

    • The distance from Tocumen International Airport to downtown is about 16 km. It takes about 30 minutes by taxi.
    • The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5 km. It takes about 20 minutes by taxi.
  • What are the most popular airlines that fly from Cali (CLO) to Panama City (PTY)?

    Airlines with flights from Cali (CLO) to Panama City (PTY): KLM, Copa Airlines and United Airlines.

How to find a cheap flight from Cali to Panama City

If you don’t know some of the key things to look out for when buying flight tickets, prices can often end up sky high or, worse, sold out! We’ve carefully compiled our six most important steps to help ensure you’re getting the best deals when planning your next journey.
1
Being flexible with your dates to get the cheapest Cali to Panama City ticket.
Tap "Date" on flight search bar to scan through the calender for Cali to Panama City airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Sat, Mar 1 at US$131 for one-way flights.
2
Compare cheap Cali to Panama City flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Cali to Panama City. The cheapest airline operating is Copa Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your Cali to Panama City route, you can easily track the price of your airline tickets from Cali to Panama City without manually checking every day.
4
Don't miss cheap Cali to Panama City flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com free app and search for cheap flight tickets from Cali to Panama City to get exclusive deals for you.

Cali to Panama City Flight Information

Cheapest nonstop flight price$104
Cheapest round-trip ticket price$244
Off-season for travelFebruary
Peak season for travelMay
Flight distance696.37 km
Average flight time1 hour 33 minutes
Popular airlineavianca